Marcelo Comini: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Identification of novel bacterial plasminogen-binding proteins in the human pathogen Mycobacterium tuberculosis

Wendy Xolalpa, Antonio J. Vallecillo, Martha Lara, Guillermo Mendoza-Hernandez, Marcelo Comini, Ralf Spallek, Mahavir Singh, Clara Espitia

Journal:

Year:

2007

Language:

english

File:

PDF, 438 KB

english, 2007

2

Lipoamide dehydrogenase is essential for both bloodstream and procyclic Trypanosoma brucei

Angela Roldán, Marcelo A. Comini, Martina Crispo, R. Luise Krauth-Siegel

Journal:

Molecular Microbiology

Year:

2011

Language:

english

File:

PDF, 1.19 MB

english, 2011

3

Valdiation of Trypanosoma brucei trypanothione synthetase as drug target

Marcelo A Comini, Sergio A Guerrero, Simon Haile, Ulrich Menge, Heinrich Lünsdorf, Leopold Flohé

Journal:

Free Radical Biology and Medicine

Year:

2004

Language:

english

File:

PDF, 834 KB

english, 2004

4

Insights into the redox biology of Trypanosoma cruzi: Trypanothione metabolism and oxidant detoxification

Florencia Irigoín, Lucía Cibils, Marcelo A. Comini, Shane R. Wilkinson, Leopold Flohé, Rafael Radi

Journal:

Free Radical Biology and Medicine

Year:

2008

Language:

english

File:

PDF, 558 KB

english, 2008

5

Preparative enzymatic synthesis of trypanothione and trypanothione analogues

Marcelo A. Comini, Natalie Dirdjaja, Mariel Kaschel, R. Luise Krauth-Siegel

Journal:

International Journal for Parasitology

Year:

2009

Language:

english

File:

PDF, 216 KB

english, 2009

6

Cytotoxic interactions of methylene blue with trypanosomatid-specific disulfide reductases and their dithiol products

Kathrin Buchholz, Marcelo A. Comini, Dirk Wissenbach, R. Heiner Schirmer, R. Luise Krauth-Siegel, Stephan Gromer

Journal:

Molecular and Biochemical Parasitology

Year:

2008

Language:

english

File:

PDF, 262 KB

english, 2008

7

Mono- and Dithiol Glutaredoxins in the Trypanothione-Based Redox Metabolism of Pathogenic Trypanosomes

Comini, Marcelo A., Krauth-Siegel, R. Luise, Bellanda, Massimo

Journal:

Antioxidants & Redox Signaling

Year:

2013

Language:

english

File:

PDF, 2.11 MB

english, 2013

8

Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism

R. Luise Krauth-Siegel, Marcelo A. Comini

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2008

Language:

english

File:

PDF, 699 KB

english, 2008

9

Iron–Sulfur Cluster Binding by Mitochondrial Monothiol Glutaredoxin-1 of Trypanosoma brucei : Molecular Basis of Iron–Sulfur Cluster Coordination and Relevance for Parasite Infectivity

Manta, Bruno, Pavan, Carlo, Sturlese, Mattia, Medeiros, Andrea, Crispo, Martina, Berndt, Carsten, Krauth-Siegel, R. Luise, Bellanda, Massimo, Comini, Marcelo A.

Journal:

Antioxidants & Redox Signaling

Year:

2013

Language:

english

File:

PDF, 4.26 MB

english, 2013

10

Determination of acidity and nucleophilicity in thiols by reaction with monobromobimane and fluorescence detection

Sardi, Florencia, Manta, Bruno, Portillo-Ledesma, Stephanie, Knoops, Bernard, Comini, Marcelo A., Ferrer-Sueta, Gerardo

Journal:

Analytical Biochemistry

Year:

2013

Language:

english

File:

PDF, 763 KB

english, 2013

11

Cloning, functional analysis, and mitochondrial localization of Trypanosoma brucei monothiol glutaredoxin-1

Filser, Michael, Comini, Marcelo A., Molina-Navarro, Maria M., Dirdjaja, Natalie, Herrero, Enrique, Krauth-Siegel, R. Luise

Journal:

Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 415 KB

english, 2008

12

Trypanothione: A unique bis-glutathionyl derivative in trypanosomatids

Manta, Bruno, Comini, Marcelo, Medeiros, Andrea, Hugo, Martín, Trujillo, Madia, Radi, Rafael

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2013

Language:

english

File:

PDF, 727 KB

english, 2013

13

Oxidovanadium(IV) and dioxidovanadium(V) complexes of tridentate salicylaldehyde semicarbazones: Searching for prospective antitrypanosomal agents

Fernández, Mariana, Becco, Lorena, Correia, Isabel, Benítez, Julio, Piro, Oscar E., Echeverria, Gustavo A., Medeiros, Andrea, Comini, Marcelo, Lavaggi, María Laura, González, Mercedes, Cerecetto, Hugo

Journal:

Journal of Inorganic Biochemistry

Year:

2013

Language:

english

File:

PDF, 1.27 MB

english, 2013

14

Synthesis of precursors and macrocycle analogs of aerucyclamides as anti-trypanosomal agents

Peña, Stella, Scarone, Laura, Medeiros, Andrea, Manta, Eduardo, Comini, Marcelo, Serra, Gloria

Journal:

Year:

2012

Language:

english

File:

PDF, 489 KB

english, 2012

15

Genetic and chemical analyses reveal that trypanothione synthetase but not glutathionylspermidine synthetase is essential for Leishmania infantum

Sousa, André F., Gomes-Alves, Ana G., Benítez, Diego, Comini, Marcelo A., Flohé, Leopold, Jaeger, Timo, Passos, Joana, Stuhlmann, Friedrich, Tomás, Ana M., Castro, Helena

Journal:

Free Radical Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

16

1H,13C and15N resonance assignment of the mature form of monothiol glutaredoxin 1 from the pathogenTrypanosoma brucei

Sturlese, Mattia, Lelli, Moreno, Manta, Bruno, Mammi, Stefano, Comini, Marcelo A., Bellanda, Massimo

Journal:

Biomolecular NMR Assignments

Year:

2015

Language:

english

File:

PDF, 461 KB

english, 2015

17

9- and 11-substituted 4-azapaullones are potent and selective inhibitors of African trypanosoma

Maiwald, Franziska, Benítez, Diego, Charquero, Diego, Dar, Mahin Abad, Erdmann, Hanna, Preu, Lutz, Koch, Oliver, Hölscher, Christoph, Loaëc, Nadège, Meijer, Laurent, Comini, Marcelo A., Kunick, Conrad

Journal:

European Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 480 KB

english, 2014

18

Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes

Comini, Marcelo A., Krauth-Siegel, R. Luise, Flohé, Leopold

Journal:

Biochemical Journal

Year:

2007

Language:

english

File:

PDF, 482 KB

english, 2007

19

A new ruthenium cyclopentadienyl azole compound with activity on tumor cell lines and trypanosomatid parasites

Rodríguez Arce, Esteban, Sarniguet, Cynthia, Moraes, Tania S., Vieites, Marisol, Tomaz, A. Isabel, Medeiros, Andrea, Comini, Marcelo A., Varela, Javier, Cerecetto, Hugo, González, Mercedes, Marques, F

Journal:

Journal of Coordination Chemistry

Year:

2015

Language:

english

File:

PDF, 813 KB

english, 2015

20

Antitumor and antiparasitic activity of novel ruthenium compounds with polycyclic aromatic ligands

Miserachs, Helena Guiset, Cipriani, Micaella, Grau, Jordi, Vilaseca, Marta, Lorenzo, Julia, Medeiros, Andrea, Comini, Marcelo A., Gambino, Dinorah, Otero, Lucía, Moreno, Virtudes

Journal:

Journal of Inorganic Biochemistry

Year:

2015

Language:

english

File:

PDF, 1.58 MB

english, 2015

21

Cytosolic Peroxidases Protect the Lysosome of Bloodstream African Trypanosomes from Iron-Mediated Membrane Damage

Hiller, Corinna, Nissen, Amrei, Benítez, Diego, Comini, Marcelo A., Krauth-Siegel, R. Luise, Beverley, Stephen M.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.38 MB

english, 2014

22

Novel ruthenium(II) cyclopentadienyl thiosemicarbazone compounds with antiproliferative activity on pathogenic trypanosomatid parasites

Fernández, Mariana, Arce, Esteban Rodríguez, Sarniguet, Cynthia, Morais, Tânia S., Tomaz, Ana Isabel, Azar, Claudio Olea, Figueroa, Roberto, Diego Maya, J., Medeiros, Andrea, Comini, Marcelo, Helena G

Journal:

Journal of Inorganic Biochemistry

Year:

2015

Language:

english

File:

PDF, 995 KB

english, 2015

23

1H,13C and15N resonance assignment of the cytosolic dithiol glutaredoxin 1 from the pathogenTrypanosoma brucei

Stefani, Monica, Sturlese, Mattia, Manta, Bruno, Löhr, Frank, Mammi, Stefano, Comini, Marcelo, Bellanda, Massimo

Journal:

Biomolecular NMR Assignments

Year:

2016

Language:

english

File:

PDF, 661 KB

english, 2016

24

A new class of thioredoxin‐related protein able to bind iron‐sulfur clusters

Bisio, Hugo, Bonilla, Mariana, Manta, Bruno, Graña, Martin, Salzman, Valentina, Aguilar, Pablo, Gladyshev, Vadim N, Comini, Marcelo A., Salinas, Gustavo

Journal:

Antioxidants & Redox Signaling

Year:

2015

Language:

english

File:

PDF, 2.08 MB

english, 2015

25

Measurement and meaning of cellular thiol:disulphide redox status

Comini, Marcelo A.

Journal:

Free Radical Research

Year:

2015

Language:

english

File:

PDF, 1.78 MB

english, 2015

26

Discovery of novel polyamine analogs with anti-protozoal activity by computer guided drug repositioning

Alberca, Lucas N., Sbaraglini, María L., Balcazar, Darío, Fraccaroli, Laura, Carrillo, Carolina, Medeiros, Andrea, Benitez, Diego, Comini, Marcelo, Talevi, Alan

Journal:

Journal of Computer-Aided Molecular Design

Year:

2016

Language:

english

File:

PDF, 2.80 MB

english, 2016

27

Glutaredoxin-deficiency confers bloodstream Trypanosoma brucei with improved thermotolerance

Musunda, Blessing, Benítez, Diego, Dirdjaja, Natalie, Comini, Marcelo A., Krauth-Siegel, R. Luise

Journal:

Molecular and Biochemical Parasitology

Year:

2015

Language:

english

File:

PDF, 2.39 MB

english, 2015

28

Selenoproteins of African trypanosomes are dispensable for parasite survival in a mammalian host

Bonilla, Mariana, Krull, Erika, Irigoín, Florencia, Salinas, Gustavo, Comini, Marcelo A.

Journal:

Molecular and Biochemical Parasitology

Year:

2016

Language:

english

File:

PDF, 1.14 MB

english, 2016

29

5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms

Orban, Oliver C.F., Korn, Ricarda S., Benítez, Diego, Medeiros, Andrea, Preu, Lutz, Loaëc, Nadège, Meijer, Laurent, Koch, Oliver, Comini, Marcelo A., Kunick, Conrad

Journal:

Bioorganic & Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

30

Catalytic mechanism of the glutathione peroxidase-type tryparedoxin peroxidase of Trypanosoma brucei

Schlecker, Tanja, Comini, Marcelo A., Melchers, Johannes, Ruppert, Thomas, Krauth-Siegel, R. Luise

Journal:

Biochemical Journal

Year:

2007

Language:

english

File:

PDF, 734 KB

english, 2007

31

In vitro activity and mode of action of distamycin analogues against African trypanosomes

Franco, Jaime, Medeiros, Andrea, Benitez, Diego, Perelmuter, Karen, Serra, Gloria, Comini, Marcelo A., Scarone, Laura

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

32

Ornithine decarboxylase or gamma-glutamylcysteine synthetase overexpression protects Leishmania (Vianna) guyanensis against antimony

Fonseca, Maisa S., Comini, Marcelo A., Resende, Bethânia V., Santi, Ana Maria M., Zoboli, Antônio P., Moreira, Douglas S., Murta, Silvane M.F.

Journal:

Experimental Parasitology

Year:

2017

Language:

english

File:

PDF, 2.30 MB

english, 2017

33

Diglycosyl diselenides alter redox homeostasis and glucose consumption of infective African trypanosomes

Franco, Jaime, Sardi, Florencia, Szilágyi, László, Kövér, Katalin E., Fehér, Krisztina, Comini, Marcelo A.

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Year:

2017

Language:

english

File:

PDF, 1.99 MB

english, 2017

34

Polyamine-based thiols in Trypanosomatids: evolution, protein structural adaptations and biological functions

Manta, Bruno, Bonilla, Mariana, Fiestas, Lucía, Sturlese, Mattia, Salinas, Gustavo, Bellanda, Massimo, Comini, Marcelo A.

Journal:

Antioxidants & Redox Signaling

Year:

2017

Language:

english

File:

PDF, 3.43 MB

english, 2017

35

Alternative Thiol-Based Redox Systems

Salinas, Gustavo, Comini, Marcelo A.

Journal:

Antioxidants & Redox Signaling

Year:

2017

Language:

english

File:

PDF, 356 KB

english, 2017

36

A glutaredoxin in the mitochondrial intermembrane space has stage-specific functions in the thermo-tolerance and proliferation of African trypanosomes

Ebersoll, Samantha, Musunda, Blessing, Schmenger, Torsten, Dirdjaja, Natalie, Bonilla, Mariana, Manta, Bruno, Ulrich, Kathrin, Comini, Marcelo A., Krauth-Siegel, R. Luise

Journal:

Year:

2018

Language:

english

File:

PDF, 1.91 MB

english, 2018

37

Binding Mode and Selectivity of Steroids towards Glucose-6-phosphate Dehydrogenase from the Pathogen Trypanosoma cruzi

Ortiz, Cecilia, Moraca, Francesca, Medeiros, Andrea, Botta, Maurizio, Hamilton, Niall, Comini, Marcelo

Journal:

Year:

2016

Language:

english

File:

PDF, 6.04 MB

english, 2016

38

New heterobimetallic ferrocenyl derivatives: Evaluation of their potential as prospective agents against trypanosomatid parasites and Mycobacterium tuberculosis

Rivas, Feriannys, Medeiros, Andrea, Rodríguez Arce, Esteban, Comini, Marcelo, Ribeiro, Camila M., Pavan, Fernando R., Gambino, Dinorah

Journal:

Journal of Inorganic Biochemistry

Year:

2018

Language:

english

File:

PDF, 705 KB

english, 2018

39

The lineage-specific, intrinsically disordered N-terminal extension of monothiol glutaredoxin 1 from trypanosomes contains a regulatory region

Sturlese, Mattia, Manta, Bruno, Bertarello, Andrea, Bonilla, Mariana, Lelli, Moreno, Zambelli, Barbara, Grunberg, Karin, Mammi, Stefano, Comini, Marcelo A., Bellanda, Massimo

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 3.25 MB

english, 2018

40

Trypanothione synthetase confers growth, survival advantage and resistance to anti-protozoal drugs in Trypanosoma cruzi

Mesías, Andrea C., Sasoni, Natalia, Arias, Diego G., Brandán, Cecilia Pérez, Orban, Oliver C.F., Kunick, Conrad, Robello, Carlos, Comini, Marcelo A., Garg, Nisha J., Paola Zago, M.

Journal:

Free Radical Biology and Medicine

Year:

2018

Language:

english

File:

PDF, 1.03 MB

english, 2018

41

New red-shifted fluorescent biosensor for monitoring intracellular redox changes

Piattoni, Claudia Vanesa, Sardi, Florencia, Klein, Florencia, Pantano, Sergio, Bollati-Fogolin, Mariela, Comini, Marcelo

Journal:

Free Radical Biology and Medicine

Year:

2019

Language:

english

File:

PDF, 4.44 MB

english, 2019

42

Glucose-6-Phosphate Dehydrogenase from the Human Pathogen Trypanosoma cruzi Evolved Unique Structural Features to Support Efficient Product Formation

Ortíz, Cecilia, Botti, Horacio, Buschiazzo, Alejandro, Comini, Marcelo A.

Journal:

Journal of Molecular Biology

Year:

2019

Language:

english

File:

PDF, 18.39 MB

english, 2019

43

Synthesis of bicyclic 1,4-thiazepines as novel anti-Trypanosoma brucei brucei agents.

Vairoletti, Franco, Medeiros, Andrea, Fontán, Pablo, Meléndrez, Jennifer, Tabárez, Carlos, Salinas, Gustavo, Franco, Jaime, Comini, Marcelo, Saldaña, Jenny, Jancik, Vojtech, Mahler, Graciela, Saiz, Ce

Journal:

Year:

2019

Language:

english

File:

PDF, 696 KB

english, 2019

44

Pt-Fe ferrocenyl compounds with hydroxyquinoline ligands show selective cytotoxicity on highly proliferative cells

Rivas, Feriannys, Medeiros, Andrea, Comini, Marcelo, Suescun, Leopoldo, Arce, Esteban Rodríguez, Martins, Marta, Pinheiro, Teresa, Marques, Fernanda, Gambino, Dinorah

Journal:

Journal of Inorganic Biochemistry

Year:

2019

Language:

english

File:

PDF, 1.44 MB

english, 2019

45

An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone

Currier, Rachel B., Ulrich, Kathrin, Leroux, Alejandro E., Dirdjaja, Natalie, Deambrosi, Matías, Bonilla, Mariana, Ahmed, Yasar Luqman, Adrian, Lorenz, Antelmann, Haike, Jakob, Ursula, Comini, Marcelo

Journal:

Year:

2019

Language:

english

File:

PDF, 10.33 MB

english, 2019

46

An essential thioredoxin-type protein of Trypanosoma brucei acts as redox-regulated mitochondrial chaperone

Currier, Rachel B., Ulrich, Kathrin, Leroux, Alejandro E., Dirdjaja, Natalie, Deambrosi, Matías, Bonilla, Mariana, Ahmed, Yasar Luqman, Adrian, Lorenz, Antelmann, Haike, Jakob, Ursula, Comini, Marcelo

Journal:

Year:

2019

File:

PDF, 10.33 MB

2019

47

A simple, robust, and affordable bioluminescent assay for drug discovery against infective African trypanosomes

Benítez, Diego, Dibello, Estefania, Bonilla, Mariana, Comini, Marcelo A.

Journal:

Drug Development Research

Year:

2020

File:

PDF, 1.93 MB

2020

48

Can drug repurposing strategies be the solution to the COVID-19 crisis?

Bellera, Carolina L., Llanos, Manuel, Gantner, Melisa E., Rodriguez, Santiago, Gavernet, Luciana, Comini, Marcelo, Talevi, Alan

Journal:

Expert Opinion on Drug Discovery

Year:

2020

File:

PDF, 1.05 MB

2020